产品详情 |
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Product Name | TM 5441 |
Description | Plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC50 = 3.58 - 60.3 μM). Increases apoptosis in human cancer cell lines. Reduces senescence and increases lifespan in mouse models of ageing (kl/kl). Inhibits L-NAME (Cat.No. 0665) induced systolic blood pressure increases, telomere length reduction and cardiac hypertrophy in mice. Renoprotective. Orally bioavailable. Purity 98%. MW (observed): 450.8 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-Chloro-2-[[2-[2-[[3-(3-furanyl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt |
Gene, Accession, CAS # | n/a |
Catalog # | 6194/10 |
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Order / More Info | TM 5441 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 24778222 |
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