| 产品详情 |
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| Antigenic Specificity | Notch1/MOTC |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Notch1/MOTC Polyclonal Antibody. • Target Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic |
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| Immunogen | KLH conjugated synthetic peptide derived from human Notch1. Immunogen Range: 2150-2200/2555 |
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| Other Names | hN1; AOS5; TAN1; AOVD1; Neurogenic locus notch homolog protein 1; Notch 1; Translocation-associated notch protein TAN-1; NOTCH1 |
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| Gene, Accession # | Gene ID: 4851, SwissProt: P46531 |
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| Catalog # | bs-1335R |
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| Price | |
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| Order / More Info | Notch1/MOTC Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Wang, Shan, et al. (2017) Clin Oral Investig. PubMed: 28866747 // Zou et al. (2018) EBioMedicine. 31:287-298. PubMed: 29764768 // Bulnes et al. (2018) Oncotarget. 9:31330-31341. PubMed: 30140373 |
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