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| Product Name | Human Hexokinase (HK) Inhibitor Screening Kit (Colorimetric) |
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| Description | Hexokinases (HK, EC: 2.7.1.1) are found in many organisms including bacteria, plants and mammals and play an important role in glucose metabolism. The Hexokinase family phosphorylates glucose and generates glucose-6-phosphate for glycolysis. Four Hexokinase isoforms (HK-I, II, III and IV) are found in numerous species. HK-I, HK-II and HK-III have low affinity for glucose, one of their natural substrates, while HK-IV show high affinity for this monosaccharide. Recent studies have found increased hexokinase activity in various human metastatic tumors. Moreover, Hexokinase II (HKII) is the main isoform of the Hexokinases and is responsible for malignant phenotypes. HKII binds to the outer mitochondrial membrane via the Voltage-Dependent Anion |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Screening/characterizing/studying potential inhibitors of human Hexokinase |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K713-100 |
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| Order / More Info | Human Hexokinase (HK) Inhibitor Screening Kit (Colorimetric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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