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Product Name | Apigenin |
Description | A naturally occurring plant flavone that displays remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties. It selectively inhibits casein kinase II (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 µM apigenin decreases the degradation of IκBα and down-regulates NF-κB levels in WEHI 231 cells. At 5 µM, it is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by 56% and 64%, respectively, in the macrophage cell line J774A.1. MW: 270. |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Chamomile; Flavone; NSC 83244; Versulin |
Gene, Accession, CAS # | CAS: 520-36-5 |
Catalog # | 2508-25 |
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Order / More Info | Apigenin from BIOVISION, INC. |
Product Specific References | n/a |
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