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| Antigenic Specificity | MAD4 |
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| Clone | OTI7F7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MAD4 Monoclonal Antibody (OTI7F7). This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. |
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| Immunogen | n/a |
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| Other Names | MXD4; MAD4; MAX dimerization protein 4; Mad4 homolog; MST149; MSTP149; bHLHc12 |
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| Gene, Accession # | Entrez: 10608; Uniprot: Q14582 |
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| Catalog # | MA5-27071 |
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| Price | |
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| Order / More Info | MAD4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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