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Antigenic Specificity | Alkaline Phosphatase/ALPL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100ug (sample available) |
Concentration | 500ug/ml. |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Alkaline phosphatase, tissue-nonspecific isozyme(ALPL) detection. Tested with WB, IHC-P in Mouse;Rat. No cross reactivity with other proteins. Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney(tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. Liver/bone/kidney alkaline phosphatase, also known as tissue-nonspecific alkaline phosphatase, acts physiologically as a lipid-anchored phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP) ectophosphatase Mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. |
Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of rat Alkaline Phosphatase(18-32aa, FVPEKEKDPSYWRQQ), different from the related mouse sequence by one amino acid. |
Other Names | Alkaline phosphatase, tissue-nonspecific isozyme;AP-TNAP;TNSALP;3.1.3.1;Alkaline phosphatase liver/bone/kidney isozyme;Alpl; |
Gene, Accession # | ALPL, UniProt: P08289 |
Catalog # | PA1004-1 |
Price | |
Order / More Info | Alkaline Phosphatase/ALPL Antibody from BOSTER BIO |
Product Specific References | n/a |
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