| 产品详情 |
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| Product Name | IT-901 |
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| Description | An inhibitor of the NF-κB subunit c-Rel; inhibits NF-κB DNA binding (IC50 = 0.1 µM); reduces TNF-α-induced NF-κB activity (IC50 = 4 µM); decreases proliferation of ABC and GCB DLBCLL cells at 3 µM; increases HO-1 expression and ROS production in mitochondria of DLBCL cells but not normal leukocytes; increases survival in a mouse model of GVHD at 24 mg/kg every other day beginning eight days after HSCT; reduces tumor growth in mouse xenograft models of EBV-induced B cell lymphoma, CLL, and Richter syndrome |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IT901 NFκB cRel HBL-1 HO1 TNFα |
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| Gene, Accession, CAS # | CAS: 1584121-99-2 |
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| Catalog # | 22298-50 |
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| Price | |
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| Order / More Info | IT-901 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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