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| Product Name | ZM 447439 |
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| Description | Novel, selective ATP-competitive inhibitor of Aurora B kinase in vitro (IC50 values are 50, 250 and 1000 nM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC50 > 10 μM). Inhibits cell division and displays selective toxicity towards proliferating tumor cells versus non-dividing cells. Purity 98%. MW (observed): 513.59 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide |
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| Gene, Accession, CAS # | CAS: 331771-20-1 |
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| Catalog # | 2458/10 |
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| Order / More Info | ZM 447439 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 17121938, 18653473, 18656424, 18843200, 19359241, 19714251, 19864462, 20619651, 20643881, 20660090, 20864688, 20937696, 20962590, 21079244, 21156286, 21239609, 21712546, 21775627, 21839059, 21874008, 22291575, 22622086, 22724006, 23029267, 23071152, 23325810, 23613471, 23712260, 24482237, 24586209, 24748653, 25601404, 26124292, 26620470, 26878753, 28640891, 28751710 |
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