| 产品详情 |
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| Antigenic Specificity | MMP24 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to MMP24. Matrix metalloproteinase-24, also known as MT5MMP or MMP25, is an enzyme that in humans is encoded by the MMP24 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. This gene may be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human MMP24, identical to the related mouse and rat sequences. |
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| Other Names | MMP-24, MTMMP5, MT5MMP, MT5-MMP, MT-MMP 5, matrix metalloproteinase 24 (membrane-inserted), membrane-type 5 matrix metalloproteinase, Membrane-type-5 matrix metalloproteinase, Membrane-type matrix metalloproteinase 5 |
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| Gene, Accession # | UniProt: Q9Y5R2 |
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| Catalog # | orb138011 |
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| Price | |
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| Order / More Info | MMP24 Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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