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| Antigenic Specificity | Early Growth Response 2 (EGR2) (aa 153-168), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Early growth response protein 2, also called EGR2 or E3 SUMO-protein ligase EGR2, is a protein that in humans is encoded by the EGR2 gene. This gene is mapped to 10q21.3. The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D(CMT1D), Charcot-Marie-Tooth disease type 4E(CMT4E), and with Dejerine-Sottas syndrome(DSS). E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human EGR2(153-168aa TMSQTQPDLDHLYSPP), different from the related rat and mouse sequences by one amino acid. |
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| Other Names | AT591|CMT1D|CMT4E|KROX20|Egr-2|Krox-20|Krox20|NGF1-B|Zfp-25|Zfp-6|KRX-20|cb427|egr2|id:ibd5073|krox20|krx20|wu:fb71h10|zgc:92210 |
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| Gene, Accession # | Gene ID: 1959,13654 |
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| Catalog # | ABIN1673651 |
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| Price | |
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| Order / More Info | Early Growth Response 2 (EGR2) (aa 153-168), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 15947997, 17717711 |
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