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Product Name | ONO-8130 |
Description | Purity >98%. ONO-8130 is an orally bioavailable antagonist of the prostaglandin E2 (PGE2 ) receptor EP (Ki = 1.9 nM)1, It exerts a more than 1,000-fold selectivity for EP1 compared with other EP receptors. ONO-8130 suppresses pain associated with cyclophosphamide-induced cystitis in mice at 0.3-30 mg/kg. It also blocks PGE2 -induced contraction and eliminates spontaneous tone of guinea pig trachea tested in tissue organ baths. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[[[2,3-dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-inden-5-yl]oxy]methyl]-benzoic acid |
Gene, Accession, CAS # | CAS: 459841-96-4 |
Catalog # | LS-H9194 |
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Order / More Info | ONO-8130 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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