| 产品详情 |
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| Product Name | Laquinimod |
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| Description | An orally bioavailable immunomodulator; induces expression of genes related to antigen presentation and inflammatory pathways in human PBMCs in vitro (0.1 µM); decreases the severity of symptoms by 91.4% and the number of relapses in mouse models of aEAE and crEAE, respectively (5 mg/kg per day); decreases T cell and macrophage density and demyelination in the spinal cord of EAE mice compared to non-treated controls (5 mg/kg per day); decreases inflammatory lesions and demyelination in the sciatic nerve in a rat EAN model (12.5 and 25 mg/kg per day); activates gene expression in the AhR pathway in splenocytes from EAE mice with no effect in AhR knockout mice (25 mg/kg per day) |
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| Size | 100 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ABR-215062 |
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| Gene, Accession, CAS # | CAS: 248281-84-7 |
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| Catalog # | 24187-100 |
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| Price | |
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| Order / More Info | Laquinimod from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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