| 产品详情 |
| Edit |   |
|---|
| Product Name | Lometrexol |
|---|
| Description | Purity >98%. Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis. Lometrexol is a folate analog antimetabolite with antineoplastic activity. At nanomolar conentrations, it inhibits GART preventing de novo purine synthesis, inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | N-[4-[2-[(6R)-2-amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin-6-yl]ethyl]benzoyl]-L-glutamic acid, (6R)-Dideazatetrahydrofolate, DDATHF, LY 264618 |
|---|
| Gene, Accession, CAS # | CAS: 106400-81-1 |
|---|
| Catalog # | LS-H8510 |
|---|
| Price | |
|---|
| Order / More Info | Lometrexol from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|