| 产品详情 |
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| Antigenic Specificity | Ankyrin-R |
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| Clone | N388A/10 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Ankyrin-R. Ankyrin-R is an anchor protein whose main role in vivo is to anchor integral membrane protein/complexes to the cytoskeleton. It was originally discovered in erythrocytes, but later to be found expressed in the brain. The gene encoding Ankyrin-R, ANK1, has a highly complex regulatory mechanism, which gives rise to a variety of different isoforms of Ankyrin-R. Recent studies in Alzheimer's Disease have shown that epigenetic dysregulation of ANK1, in combination of several other proteins including Trem-2, could be a contributing factor of increased TNFA expression and neuroinflammation1. |
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| Immunogen | n/a |
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| Other Names | ANK1, Ankyrin-R, |
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| Gene, Accession # | Gene ID: 286, 11733, 306570 |
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| Catalog # | 857701 |
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| Price | |
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| Order / More Info | Ankyrin-R Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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