| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Caspase Recruitment Domain Family, Member 8 (CARD8) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq] Synonyms: CARD8, CARDINAL, DACAR, DKFZp779L0366, Dakar, FLJ18119, FLJ18121, KIAA0955, MGC57162, NDPP, NDPP1, TUCAN |
|---|
| Immunogen | Recombinant protein of human CARD8 |
|---|
| Other Names | CARD8|CARDINAL|DACAR|DAKAR|NDPP|NDPP1|TUCAN |
|---|
| Gene, Accession # | Gene ID: 22900 |
|---|
| Catalog # | ABIN1512669 |
|---|
| Price | |
|---|
| Order / More Info | Caspase Recruitment Domain Family, Member 8 (CARD8) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|