| 产品详情 |
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| Product Name | Sivelestat |
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| Description | Sivelestat (ONO-5046) is a potent neutrophil elastase inhibitor. It acts as a substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase). Sivelestat displays >100-fold greater selectivity over pancreatic elastase (IC50 = 5.6 µM). It does not inhibit trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G even at concentrations as high as 100 µM. MW: 434.46. Purity ≥97% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(2-(4-(pivaloyloxy)phenylsulfonamido)benzamido)acetic acid; ONO-5046 |
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| Gene, Accession, CAS # | CAS: 127373-66-4 |
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| Catalog # | B2144-5 |
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| Order / More Info | Sivelestat from BIOVISION, INC. |
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| Product Specific References | n/a |
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