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| Product Name | Gliotoxin |
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| Description | Immunosuppressive agent; blocks phagocytosis, cytokine production and proliferation of T and B cells. Non-competitively inhibits chymotrypsin-like activity of 20S proteasome; prevents degradation of IκBα, an endogenous blocker of NF-κB. Also inhibits farnesyltransferase and geranylgeranyltransferase I (IC50 values are 80 and 17 μM respectively) and displays antitumor activity against breast cancer in vivo. MW (observed): 326.38. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3R,5aS,6S,10aR)-2,3,5a,6-Tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione. Aspergillin |
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| Gene, Accession, CAS # | CAS: 67-99-2 |
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| Catalog # | 2637/1 |
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| Price | |
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| Order / More Info | Gliotoxin from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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