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| Product Name | NEIL2, 1-332aa, Human, His tag, E Coli |
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| Description | MW: 39.4 kDa (356aa), confirmed by MALDI-TOF. Purity >85% by SDS-PAGE. Endonuclease 8-like 2, also known as NEIL2, belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. It has negligible or undetectable activity with 8-oxoguanine, thymine glycol, 2-hydroxyadenine, hypoxanthine, an |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Endonuclease 8-like 2; NEH2; NEI2; Nei-like protein 2] |
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| Gene, Accession, CAS # | NEIL2, Gene ID: 252969, Accession: NP_659480 |
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| Catalog # | MBS204305 |
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| Order / More Info | NEIL2, 1-332aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Hazra TK., et al. (2002) J Biol Chem. 277 (34):30417-20.; Das D., et al. (2007) J Biol Chem. 282 (39):28474-84. |
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