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| Product Name | NEIL1, 1-390aa, Human, His tag E Coli |
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| Description | MW: 45.8 kDa (410aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. Recombinant human NEIL1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography. |
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| Size | 0.01 mg, 0.05 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Endonuclease 8-like 1; FLJ22402; FPG1; hFPG1; NEI1] |
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| Gene, Accession, CAS # | NEIL1, Gene ID: 79661, Accession: NP_078884 |
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| Catalog # | MBS204436 |
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| Order / More Info | NEIL1, 1-390aa, Human, His tag E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Hazra T.K. et al. (2002) J. Biol.Chem. 277: 30417-30420.; Dou H. et al. (2003) J. Biol.Chem. 278: 49679-49684. |
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