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| Product Name | Recombinant Mouse Granzyme A (Gzma) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 39.6kDa. Full Length of Mature Protein: 29-260aa. N-terminal 6xHis-B2M-tagged. Mus musculus (Mouse). Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Autocrine thymic lymphoma granzyme-like serine protease; CTLA-3; Fragmentin-1; T cell-specific serine protease 1 |
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| Gene, Accession, CAS # | Gzma, UniProt: P11032 |
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| Catalog # | RPC20502 |
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| Order / More Info | Recombinant Mouse Granzyme A (Gzma) from BIOMATIK |
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| Product Specific References | n/a |
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