| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | c-Cbl |
|---|
| Clone | 3B12 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | c-Cbl Monoclonal Antibody (3B12). The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. |
|---|
| Immunogen | n/a |
|---|
| Other Names | C-CBL, CBL2, NSLL, RNF55, E3 ubiquitin-protein ligase CBL; RING finger protein 55; casitas B-lineage lymphoma proto-oncogene; oncogene CBL2; proto-oncogene c-Cbl; signal transduction protein CBL |
|---|
| Gene, Accession # | Entrez: 12402, 500985, 867; Uniprot: P22681, P22682 |
|---|
| Catalog # | MA5-15885 |
|---|
| Price | |
|---|
| Order / More Info | c-Cbl Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|