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| Product Name | CGP 55845 hydrochloride |
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| Description | Potent, selective GABAB receptor antagonist (IC50 = 5 nM) that prevents agonist binding (pKi = 8.35) and inhibits GABA and glutamate release (pEC50 values are 8.08 and 7.85 respectively). Inhibits GABAB responses to baclofen (IC50 = 130 nM in an isoproterenol assay) and potentiates the hypoglycemic response to glucose in vitro. Purity 98%. MW (observed): 438.71 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid hydrochloride |
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| Gene, Accession, CAS # | CAS: 149184-22-5 |
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| Catalog # | 1248/50 |
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| Order / More Info | CGP 55845 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 11082110, 15140926, 15673670, 15813991, 16135550, 16301180, 16775144, 17045484, 17502847, 17689570, 17706254, 18046308, 18216224, 18216231, 18354024, 18667157, 18687967, 18715900, 18768644, 18789344, 18832425, 18930747, 19198604, 19535596, 20071517, 20074214, 20427660, 20445035, 21145007, 21173075, 21249195, 21325532, 21526163, 21602822, 21623363, 21712833, 21858222, 21976507, 22153080, 22218089, 22308379, 22347811, 22496577, 22593048, 22728089, 22836254, 22914654, 22956823, 22968812, 23029198, 23325252, 23387435, 23443540, 23935583, 23974706, 24009558, 24062646, 24107948, 24169802, 24474905, 24653676, 24962993, 25114926, 25162235, 25242218, 25540024, 25716863, 25852468, 25852553, 25855695, 25926446, 26245975, 26269634, 26308580, 26418566, 26472558, 26755335, 26769224, 27345695, 27383597, 27687783, 27721466, 27821575, 27886263, 28300552, 30253088, 30301899 |
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