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| Product Name | Sirtuin Activity Assay Kit (Fluorometric) |
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| Description | Sirtuins are a class of proteins that possess either histone deacetylase or mono-ribosyltransferase activity. Sirtuins are localized in the cytoplasm, nucleus, nucleolus as well as mitochondria. They are associated with aging, cellular protection, sugar metabolism and cell cycle regulation. Unlike other known protein deacetylases, which simply hydrolyze acetyl-lysine residues, the sirtuin-mediated deacetylation reaction hydrolyzes acetyl-lysine and NAD. This hydrolysis yields the deacetylated substrate, O-acetyl-ADP-ribose and nicotinamide, itself an inhibitor of sirtuin activity. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. In BioVision's Sirtuin Activi |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Detection of Sirtuin Activity in variety of samples |
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| Other Names | Sirt Activity Assay Kit (Fluorometric) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K324-100 |
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| Order / More Info | Sirtuin Activity Assay Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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