| 产品详情 |
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| Product Name | Damnacanthal |
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| Description | Potent inhibitor of p56lck tyrosine kinase activity (IC50 = 17 nM for inhibition of autophosphorylation). Displays 7- to 20-fold selectivity over p59fyn and p60src tyrosine kinases, > 40-fold selectivity over c-ErbB2, EGF- and insulin-receptor tyrosine kinases, and > 100-fold selectivity over PKA and PKC. Mobilizes intracellular Ca2+ in dermal fibroblasts and inhibits Ras function. Also inhibits LIMK1/2, as well as migration and invasion of breast cancer cells in vitro. Purity 98%. MW (observed): 282.25 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 9,10-Dihydroxy-3-hydroxy-1-methoxy-9,10-dioxo-2-anthracenecarboxaldehyde |
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| Gene, Accession, CAS # | CAS: 477-84-9 |
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| Catalog # | 1936/1 |
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| Price | |
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| Order / More Info | Damnacanthal from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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