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| Product Name | Terfenadine |
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| Description | Histamine H1 receptor antagonist. Also blocks KV11.1 (hERG) and Kir6 (KATP) channels (IC50 values are 204 nM and 1.2 μM respectively). Inhibits the delayed rectifier K+ current (IKr) in guinea pig ventricular myocytes (IC50 = 50 nM). Activity prolongs QT and induces Torsades de pointes (TdP); cardiotoxic in vivo. Purity 98%. MW (observed): 471.67 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol |
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| Gene, Accession, CAS # | CAS: 50679-08-8 |
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| Catalog # | 3948/50 |
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| Price | |
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| Order / More Info | Terfenadine from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21873469, 23328157 |
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