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Product Name | Antisauvagine-30 |
Description | Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2β cells (pA2 = 8.49). Prevents stress-enhanced fear conditioning and MEK 1/2-dependent activation of ERK1/2 in mice in vivo. MW (observed): 3650.29. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [D-Phe11,His12]-Sauvagine (11-40) |
Gene, Accession, CAS # | CAS: 220673-95-0 |
Catalog # | 2071/1 |
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Order / More Info | Antisauvagine-30 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25898242, 26074770 |
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