| 产品详情 |
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| Product Name | ARRY 520 trifluoroacetate |
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| Description | Potent kinesin spindle protein (KSP) inhibitor (IC50 = 6 nM); selective for KSP over >250 other receptors and kinases at a concentration of 10 μM. Displays robust antitumor activity in bortezomib-resistant xenografts either alone or in combination with bortezomib. Induces degradation of Mcl-1; exhibits comparable cytotoxic activity to taxol (Cat. No. 1097) in epithelial ovarian cancer cells. Active in vivo. Purity 98%. MW (observed): 420.48 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide trifluoroacetate. Filanesib |
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| Gene, Accession, CAS # | CAS: 885060-09-3 |
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| Catalog # | 4676/10 |
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| Order / More Info | ARRY 520 trifluoroacetate from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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