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| Product Name | AS 2444697 |
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| Description | Potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC50 = 21 nM). Displays 30-fold selectivity for IRAK4 over IRAK1. Inhibits LPS-induced TNF-α and IL-6 production in PBMCs in vitro. Renoprotective and anti-inflammatory in a rodent model of chronic kidney disease. Purity 98%. MW (observed): 432.86 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride |
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| Gene, Accession, CAS # | CAS: 1287665-60-4 |
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| Catalog # | 5430/10 |
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| Price | |
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| Order / More Info | AS 2444697 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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