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| Product Name | Fostriecin sodium salt |
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| Description | Potent inhibitor of protein phosphatase types 2A (PP2A) and 4 (PP4) with IC50 values of 1.5 nM and 3 nM respectively. Also exhibits weaker inhibition of topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM) with no apparent inhibition of protein phosphatase type 2B (PP2B). Active in vivo. Originally identified as an antitumor antibiotic from Streptomyces pulveraceous. Purity 98%. MW (observed): 452.37 |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt |
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| Gene, Accession, CAS # | CAS: 87860-39-7 |
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| Catalog # | 1840/50U |
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| Order / More Info | Fostriecin sodium salt from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19906957, 20181591, 20969573, 24089494, 25031403, 29930108 |
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