| 产品详情 |
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| Product Name | FR 180204 |
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| Description | Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30 μM. Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1 μM). Purity 98%. MW (observed): 327.34 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine |
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| Gene, Accession, CAS # | CAS: 865362-74-9 |
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| Catalog # | 3706/50 |
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| Price | |
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| Order / More Info | FR 180204 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22683469, 24086109, 25052197, 25195011, 25425646, 25547114, 25738359, 27659207 |
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| 产品资料 |
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