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| Product Name | PD 166285 dihydrochloride |
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| Description | Potent inhibitor of the tyrosine kinases c-Src, fibroblast growth factor receptor 1 (FGFR1), and platelet-derived growth factor receptor β (PDGFRβ) (IC50 values are 8.4, 39.3 and 98.3 nM respectively). Also inhibits the checkpoint kinases Wee1 and Myt1; abolishes Cdc2 phosphorylation in numerous tumor cell lines and abrogates the G2 checkpoint. Purity 99%. MW (observed): 585.35 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride |
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| Gene, Accession, CAS # | CAS: 212391-63-4 |
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| Catalog # | 3785/1 |
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| Price | |
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| Order / More Info | PD 166285 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21795279 |
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