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| Product Name | PDD 00017273 |
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| Description | Potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor (IC50 = 26 nM). Exhibits >350-fold selectivity for PARG over a panel of ion channels, enzymes and receptors, including PARP1 and ARH3. Maintains PAR chains and induces DNA double-stranded breaks in cells following DNA damage. Decreases colony formation of ZR-75-1 BRCA1 WT cells. Cell permeable. Purity 98%. MW (observed): 514.62 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[(1,3-Dimethyl-1H-pyrazol-5-yl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide |
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| Gene, Accession, CAS # | CAS: 1945950-21-9 |
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| Catalog # | 5952/10 |
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| Order / More Info | PDD 00017273 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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