| 产品详情 |
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| Product Name | Eeyarestatin I |
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| Description | Potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD). Specifically targets the p97-associated deubiquinating process (PAD) and inhibits ataxin-3 (atx3)-dependent deubiquitination. Also inhibits Sec61-mediated protein translocation at the ER. Displays cytotoxic activity preferentially against cancer cells; induces cell death via the proapoptotic protein NOXA. Purity 98%. MW (observed): 630.44 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(4-Chlorophenyl)-4-[[[(4-chlorophenyl)amino]carbonyl]hydroxyamino]-5,5-dimethyl-2-oxo-1-imidazolidineacetic acid 2-[3-(5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide |
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| Gene, Accession, CAS # | CAS: 412960-54-4 |
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| Catalog # | 3922/10 |
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| Price | |
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| Order / More Info | Eeyarestatin I from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25406314, 26074080, 27558430, 30254296 |
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| 产品资料 |
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