| 产品详情 |
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| Product Name | Eggmanone |
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| Description | Potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 = 72 nM). Exhibits >40-fold selectivity over PDE3, PDE10, and PDE11. Displays no significant activity on a panel of 442 kinases, 158 GPCRs and 21 phosphatases. Suppresses hedgehog signaling through PDE antagonism, downstream of smoothened signaling. Reduces transcription of Gli1 and Ptc1. Purity 98%. MW (observed): 416.58 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5,6,7,8-Tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-[1]benzothieno[2,3-d]pyrimidin-4(3H)-one |
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| Gene, Accession, CAS # | CAS: 505068-32-6 |
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| Catalog # | 5695/10 |
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| Price | |
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| Order / More Info | Eggmanone from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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