| 产品详情 |
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| Antigenic Specificity | Caspase-10 |
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| Clone | 25C2 |
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| Host Species | Rat |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Caspase-10. There are two types of apoptotic caspases, initiator (apical) caspases and effector (executioner) caspases. Caspase 10 is one of the initiator caspases that cleave inactive pro-forms of effector caspases, thereby activating them. Four isoforms, namely Caspase-10a,-10 b,-10c,and -10d have been identified. They derived from a single chain polypeptide proenzyme but have different mature large and small subunits by cleavage. After the death ligand-receptor binding, caspade-10 has joined the multimeric Fas/TNF receptor complex and gets cleaved. The cleaved caspase-10 further acts on other effector caspases to initiate the caspase cascade. |
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| Immunogen | His tagged bacterial fusion protein of caspase-10 p20 |
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| Other Names | Mch4 |
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| Gene, Accession # | Gene ID: 843 |
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| Catalog # | 645202 |
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| Price | |
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| Order / More Info | Caspase-10 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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