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| Product Name | Ro 106-9920 |
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| Description | Inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. Purity 99%. MW (observed): 245.26 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-(Phenylsulfinyl)tetrazolo[1,5-b]pyridazine |
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| Gene, Accession, CAS # | CAS: 62645-28-7 |
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| Catalog # | 1778/50 |
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| Price | |
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| Order / More Info | Ro 106-9920 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23536315, 25914608, 26714634 |
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