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| Antigenic Specificity | B-Cell CLL/lymphoma 3 (BCL3) (aa 199-216), (Middle Region) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. |
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| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human Bcl3(199-216aa MALDRHGQTAAHLACEHR), different from the related rat and mouse sequences by one amino acid. |
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| Other Names | BCL3|AI528691|Bcl-3|BCL4|D19S37 |
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| Gene, Accession # | Gene ID: 602,680611 |
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| Catalog # | ABIN1673047 |
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| Price | |
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| Order / More Info | B-Cell CLL/lymphoma 3 (BCL3) (aa 199-216), (Middle Region) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 1501714 |
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