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| Product Name | HLI 373 |
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| Description | Inhibitor of Hdm2 ubiquitin ligase (E3). Blocks Hdm2-mediated ubiquitylation and proteasomal degradation of p53; activates p53-dependent transcription. Induces apoptosis in several tumor cell lines that express wild-type p53 such as LOX-IMVI, A549, HT1080 and U2OS. Purity 99%. MW (observed): 414.33 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-[[3-Dimethylamino)propyl]amino]-3,10-dimethylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione dihydrochloride |
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| Gene, Accession, CAS # | CAS: 502137-98-6 |
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| Catalog # | 3503/10 |
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| Price | |
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| Order / More Info | HLI 373 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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