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| Product Name | Cladribine |
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| Description | Adenosine deaminase (ADA)-resistant analog of deoxyadenosine. Exhibits anti-leukemic activity; Inhibits cell growth of lymphoid and myeloid neoplasm (IC50 = 20 - 87 nM). Pro-apoptotic; induces DNA double-strand breaks. Also inhibits ribonuclease reductase (IC50 = 0.11 - 0.28 μM). Displays activity in vitro and in vivo. Orally bioavailable. Purity 99%. MW (observed): 285.69 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R,3S,5R)-5-(6-Amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxalan-3-ol. 2-Chloro-2'-deoxyadenosine |
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| Gene, Accession, CAS # | CAS: 4291-63-8 |
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| Catalog # | 5292/10 |
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| Price | |
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| Order / More Info | Cladribine from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26571499 |
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| 产品资料 |
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