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Antigenic Specificity | Amyloid Precursor Protein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, IHC-P, IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APP/Amyloid Precursor Protein Antibody. • Target Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosi |
Immunogen | KLH conjugated synthetic peptide derived from human of human APP. Immunogen Range: 380-430/770 |
Other Names | AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; Amyloid beta A4 protein; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; PreA4; Protease nexin-II; A4 |
Gene, Accession # | Gene ID: 351, SwissProt: P05067 |
Catalog # | bs-0112R |
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Order / More Info | Amyloid Precursor Protein Antibody from BIOSS ANTIBODIES |
Product Specific References | Potter Andrew S., et al. (2015) PLoS ONE 10(7): e0132662. PubMed: 26168040 // Wang, Chengke, et al. (2015) Anal Biochem. PubMed: 26299647 |
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