| 产品详情 |
| Edit |   |
|---|
| Product Name | INDY |
|---|
| Description | DYRK1A/B inhibitor (IC50 values are 0.23 and 0.24 μM, for DYRK1B and DYRKA respectively). Binds at the ATP-binding cleft of the enzyme. Reverses aberrant tau-phosphorylation and rescues repressed calcineurin/NFAT signaling. Impairs the self-renewal capacity of subventricular zone neural stem cells. Also available as a prodrug, proINDY (Cat. No. 4998). Purity 98%. MW (observed): 235.3 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone |
|---|
| Gene, Accession, CAS # | CAS: 1169755-45-6 |
|---|
| Catalog # | 4997/10 |
|---|
| Price | |
|---|
| Order / More Info | INDY from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 25751815, 25878110, 27483355 |
|---|
| 产品资料 |
|
|