| 产品详情 |
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| Product Name | 5-Iodo-A-85380 dihydrochloride |
| Description | A highly potent and subtype-selective agonist for the α4β2 and α6β2 nicotinic acetylcholine receptors. Activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes, corresponding to α6β2 and α4β2 (EC50 values are 12.7 and ~35 nM respectively). ~5000-, 25000- and 140000-fold selective over α3β4, α7 and muscle nAChR receptors respectively. Precursor also available.. Purity 99%. MW (observed): 363.03 |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridine dihydrochloride |
| Gene, Accession, CAS # | CAS: 1217837-17-6 |
| Catalog # | 1518/10 |
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| Order / More Info | 5-Iodo-A-85380 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19545536, 24728867, 25906356 |
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