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| Product Name | GSK4112 |
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| Description | A synthetic agonist for REV-ERBα (EC50 = 0.4 µM) that mimics the action of heme; at 10 µM inhibits the expression of the circadian target gene bmal1 and reduces glucose output by 30% in mouse primary hepatocytes by repressing the expression of several gluconeogenic genes |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | REV-ERBα nuclear hormone receptors circadian rhythm adipogenesis lipids metabolisms inflammation hemes NCoR HDAC3 transcriptional repression agonists gluconeogenesis GSK 4112 REVERBα inhibits inhibitors inhibiting bmal1 ovaries metabolism |
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| Gene, Accession, CAS # | CAS: 1216744-19-2 |
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| Catalog # | 11931-50 |
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| Order / More Info | GSK4112 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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