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| Product Name | VU 0285683 |
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| Description | Negative allosteric modulator of mGlu5 receptors. Displays high affinity for the MPEP (Cat. No. 1212) binding site; acts as a full antagonist and blocks the glutamate response to mGlu5 (IC50 = 24.4 nM). Selective for mGlu5 over mGlu1, mGlu3 and mGlu4. Exhibits anxiolytic activity in rodent models of anxiety. Analog available (Cat. No. 4323). Purity 98%. MW (observed): 266.23 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-Fluoro-5-[3-(2-pyridinyl)-1,2,4-oxadiazol-5-yl]-benzonitrile |
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| Gene, Accession, CAS # | CAS: 327056-22-4 |
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| Catalog # | 4381/50 |
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| Price | |
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| Order / More Info | VU 0285683 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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