| 产品详情 |
| Edit |   |
|---|
| Product Name | Rottlerin |
|---|
| Description | Originally reported to inhibit PKC isoforms. Also reported to inhibit CAM kinase III. However, recently shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively). Also shown to act as a direct mitochondrial uncoupler. Thought to stimulate autophagy by targeting upstream mTORC1 control pathways. MW (observed): 516.55. |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone |
|---|
| Gene, Accession, CAS # | CAS: 82-08-6 |
|---|
| Catalog # | 1610/10 |
|---|
| Price | |
|---|
| Order / More Info | Rottlerin from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 20395409, 21593487, 23799098, 23995289, 24748172, 27111842 |
|---|
| 产品资料 |
|
|