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| Product Name | TCN 237 dihydrochloride |
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| Description | Highly potent GluN2B (formally NR2B) selective NMDA receptor antagonist (Ki = 0.8 nM); blocks GluN2B-mediated calcium influx in Ltk cells (Ki = 9.7 nM). Selective for GluN2B subunit over α1-adrenergic receptors and hERG channels (IC50 values are 730 nM and 2900 nM respectively). Displays efficacy in the rat carrageenan-induced mechanical hyperalgesia assay. Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions. Purity 98%. MW (observed): 412.33 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[4-[(2-Fluorophenyl)methyl]-1-piperidinyl]methyl]-1H-benzimidazol-6-ol dihydrochloride |
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| Gene, Accession, CAS # | CAS: 700878-19-9 |
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| Catalog # | 4072/10 |
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| Price | |
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| Order / More Info | TCN 237 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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