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| Product Name | (-)-Xestospongin C |
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| Description | Reported inhibitor of IP3-dependent Ca2+ release. Inhibits bradykinin -induced Ca2+ release in PC12 cells and attenuates PHP-induced IL-2 production in Jurkat T cells. Exhibits no effect on ryanodine receptor-mediated Ca2+ release in PC12 cells. Does not interact with the IP3 binding site. Recently shown to be an ineffective antagonist of IP3-evoked Ca2+ release in IP3 receptor expressing DT40 cells. Cell permeable. MW (observed): 446.71. |
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| Size | 10 ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine. XeC |
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| Gene, Accession, CAS # | CAS: 88903-69-9 |
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| Catalog # | 1280/10U |
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| Price | |
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| Order / More Info | (-)-Xestospongin C from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22045699, 22114277, 23269840, 24470488, 24687992, 25009258, 25314270, 25558061, 26269634, 26489864, 26667040 |
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