| 产品详情 |
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| Antigenic Specificity | N-cadherin |
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| Clone | 8C11 |
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| Host Species | Mouse |
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| Reactive Species | hamster, human, mouse, rabbit |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50 - 1:200, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 5 µg, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | N-cadherin Monoclonal Antibody (8C11). N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five e |
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| Immunogen | n/a |
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| Other Names | Cadherin-2, Neural-cadherin, CDw325 antigen, CD325, CDHN, NCAD, Cadherin-N |
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| Gene, Accession # | Entrez: 1000, 100344571, 100689204, 12558; Uniprot: P15116, P19022 |
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| Catalog # | MA1-2002 |
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| Price | |
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| Order / More Info | N-cadherin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12604612, 20197094, 25812522 |
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