| 产品详情 |
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| Antigenic Specificity | N-cadherin |
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| Clone | NCD-2 |
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| Host Species | Rat |
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| Reactive Species | chicken, Xenopus laevis |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Inhibition Assays: 100 µg/mL, Western Blot: 1-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | N-cadherin Monoclonal Antibody (NCD-2). N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five |
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| Immunogen | n/a |
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| Other Names | Cadherin-2, Neural-cadherin, CDw325 antigen, CD325, CDHN, NCAD, Cadherin-N |
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| Gene, Accession # | Entrez: 414745; Uniprot: P10288 |
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| Catalog # | 13-2100 |
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| Price | |
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| Order / More Info | N-cadherin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11124112, 11274361, 12482923, 12645933, 15292404, 15649477, 1638632, 17081713, 19162191, 19843154, 23626818, 24942669 |
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