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Product Name | Recombinant Human Interleukin-1 receptor antagonist protein (IL1RN) (Active) |
Description | Purity > 96% as determined by SDS-PAGE and HPLC. MW: 17.1kDa. Full Length of Mature Protein: 26-177aa. tag-Free. Homo sapiens (Human). Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. {ECO:0000269|PubMed:7775431}. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | IL-1RN, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra |
Gene, Accession, CAS # | IL1RN,IL1F3,IL1RA, UniProt: P18510 |
Catalog # | RPC26490 |
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Order / More Info | Recombinant Human Interleukin-1 receptor antagonist protein (IL1RN) (Active) from BIOMATIK |
Product Specific References | n/a |
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